Determination of Chloroquine, Hydroxychloroquine and its Metabolite DesethylHydroxychloroquine in Plasma Samples by LC-MS/MS

Abstract:

This application note describes the analysis of these two drugs together with the metabolite Desethyl Hydroxychloroquine (DHCQ) from various biological matrices. The method was developed by Dr. Thomas Lanot from the Institut Fédératif de Biologie – CHU de Toulouse in France. The isocratic method allows for a fast and reliable quantification with a LOQ of 10 µg/L.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical

Techniques:

HPLC / UHPLC

Brands:

Kinetex

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