USP Assay and Organic Impurities (LC-UV) for Chloroquine Phosphate
- Abstract:
- In this application for the LC-UV assay of chloroquine phosphate, the mobile phase conditions outlined by the USP for Chloroquine Phosphate were used. Two C18 (USP L1) columns containing different particle morphologies, but the same 150 x 4.6 mm dimension and 5 μm particle size, were compared. The standard solution (0.3 mg/mL of Chloroquine Phosphate in mobile phase) and system suitability solution (2.0 μg/mL each of USP Chloroquine Phosphate RS, USP Phenol RS, USP Hydroxychloroquine Sulfate RS, USP Chloroquine Related Compound A RS, USP Chloroquine Related Compound D RS, USP Chloroquine Related Compound E RS, and USP Chloroquine Related Compound G RS in Mobile phase) were prepared in accordance with the USP monograph.
- Document Type:
- Technical Notes
- Industries:
- Pharmaceutical/Biopharmaceutical
- Techniques:
- HPLC / UHPLC
- Brands:
- Kinetex Luna
- PDF Link:
- Click here